High Content Cellular Imaging
• Improving Spectral Properties of Engineered Fluorescent Proteins
• Tracking Receptor Activation and Signal Transduction Pathways
• High Content Image Based Screening 

Visualizing Protein Dynamics 
• Visualization of Protein Interactions in Living Cells 
• Towards a Global Pharmacology of the Cell 
• Self Labeling Protein in Intracellular Studies
• Live Cell Imaging

Functional Silencing with RNA
• siRNA-mediated Gene Silencing with GFP 
• Genome-scale Functional Profiling Through Image-based Analysis
• Functional siRNA Screening of the Cell Cycle

Visualizing the activity of both drugs and targets in the context of a living cell are critical to the effective evaluation of drug action and efficacy. Fluorescent proteins are fluorescent probes that attach to a protein of interest, and allow real-time, non-invasive and representative reporting in living cells. Using fluorescent proteins as reporters provides a new window into the machinery of a cell, and allows the selection and investigation of compounds that address specific biochemical pathways. The applications of fluorescent proteins in drug discovery allow powerful insights into cellular imaging, early stage target characterization, receptor biology, protein-protein interaction, high content screening assays, and in vivo diagnostics. Fluorescent proteins have proven to be instrumental in observing and monitoring the effects of RNAi and gene knock-down on biochemical pathways. The advantages of using fluorescent proteins are numerous. Come to the conference to hear about the latest constructs and applications of this reporter molecule and how it can enable you to improve your success rate in evaluating drug candidates.