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Overview
Selection systems of biologically-active molecules are essential to pipeline of novel protein therapeutics which can be directed against
targets that are intractable to small molecules. Phage display and related techniques such as mRNA, bacteria, yeast, antibody, ribosome
display offer the ability to generate and select ligands against biologic mechanisms, and engineer drug-like properties into candidates
that show high affinity and specificity. Novel scaffolds will be considered for many reasons, including the ease of synthesis and
the ability to address new drug targets. This meeting will focus on the technologies used to optimize protein and peptide entities
against targets, and the refinement of these methods for clinical application against cancer, AIDS, autoimmune, infection, and other
diseases.
| Topics may include, but are not limited to: |
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• Recombination-Based Cloning
• Antibody Alternatives
• Novel Scaffolds for Designing Biologically
Active Molecules
• Optimization of Ligands
• Protein Medicinal Chemistry- Addressing
Immunogenicity, Stability and Half-Life
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• Synthetic Amino Acids and Peptides
• Mapping Functional Sites on Target Proteins
• Improved Methods of Screening Epitope
Libraries
• Bridging Technologies With Applications
• Production of Humanized, Complex
Therapeutic Proteins |
If you would like to submit a proposal to give a presentation or display a poster at this meeting please send us, by fax or email, a title
and brief 3-5 sentence summary of a proposed topic in the area of display methodologies by October 14, 2005. All proposals are subject
to review by the Scientific Advisory Committee to ensure the overall quality of the conference program.
Click
here to submit a proposal
For more information, please contact, fax or e-mail submissions to:
Christina Lingham, Cambridge Healthtech Institute
Phone: 617 630-1364 • Fax: 617 630-1325 • Email: clingham@healthtech.com
For exhibits and sponsorship information, please contact:
Carol Dinerstein, Manager of Business Development • Phone: 781-972-5471
• E-mail: dinerstein@healthtech.com
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