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Post-Conference Events Friday, February 3


Extend your conference experience by adding on an extra day of the 
co-located High-Content Analysis 2006 program.*

Visit www.highcontentanalysis.com for more information.

7:30-8:15 Technology Workshop 
Sponsorship Available. Contact: Carol Dinerstein at 781-972-5471 or dinerstein@healthtech.com.

ASSAY DESIGN FOR HCA

NEURONAL SCREENING

8:30-9:00 A Comparison of Different High-Content Methodologies as Applied to Lead Discovery and Target Validation
Mrs. Judy Dziuba, Senior Scientist, Lead Discovery, Bayer Healthcare AG
Applying the Power of HCA to Neuronal Screening
Dr. John Dunlop, Director, Discovery Neuroscience, Wyeth Research
9:00-9:30 Assay Development for the Targeting of Distinct Cellular Phenotypes
Dr. Oliver Poeschke, Scientist, Central Assay Development & Screening, Merck KGaA
Screening Chemical Libraries to Identify Regulators of CNS Axon Growth and Branching
Dr. John Bixby, Professor, Pharmacology/Miami Project, University of Miami Miller School of Medicine
9:30-10:00 An Integrated Robotic Platform for High-Content Screening: Analysis of GPCR Internalization and Cellular Signaling
Dr. Ralf Heilker, Senior Scientist, Integrated Lead Discovery, Boehringer Ingelheim Pharma GmbH & Co. KG
Technologically Integrated Assay Approaches to Complex Signaling Events 
Dr. Vahri Beaumont, Senior Research Biologist, Automated Imaging and Electrophysiology, Merck Sharp and Dohme
10:00-10:30 Coffee Break
10:30-11:00 Phenotypic Assays for Oncology Drug Discovery
Dr. Bonnie Howell, Senior Research Biochemist, Cancer Research, Merck & Co., Inc.
High-Content Secondary Screening of Apoptosis in Neuronal Cell Lines
Dr. Dorothea Haasen, Research Scientist, Integrated Lead Discovery, Boehringer Ingelheim Pharma GmbH&Co. KG
11:00-11:30 Developing and Validating a High-Content Screen for Intracellular Cholesterol Distribution
Dr. Fred Maxfield, Professor and Chairman, Department of Biochemistry, Weill Medical College of Cornell University
High-Content Analysis of Human Embryonic Stem Cell Growth and Pluripotency
Dr. Paul Sammak, Associate Professor, Pittsburgh Development Center at the Magee Women’s Research Institute, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh
11:30-12:00 High-Content Analysis for DNA Content
Mr. Aidas Kriauciunas, Research Scientist, Integrative Biology, Eli Lilly and Company
Development of an In Vitro Model for Nerve Injury on the Discovery-1 Platform
Dr. Mark Schurdak, Group Leader, Biological Screening, Abbott Laboratories
12:00-12:30 Finding Content in High-Content Data: Two Case Studies for Target-Specific and Phenotypic HCS Assays
Dr. Andreas Vogt, Research Assistant Professor, Pharmacology, University of Pittsburgh 
Automated Fluorescent Imaging in Live Brain Tissue Explants: Challenges for Ultra-High-Content Screening (HCS) in Drug Discovery for Neurodegenerative Diseases
Mr. Oscar Trask, Associate in Research, Center for Drug Discovery, Duke University Medical Center

12:30-2:00 Lunch (on your own) or Technology Workshop
Additional Sponsorship Available. Contact: Carol Dinerstein at 781-972-5471 or dinerstein@healthtech.com.

LIVE-CELL IMAGING

2:00-2:30 Utilizing Live-Cell Imaging for Target Validation and Lead Optimization
Dr. Stefan Prechtl, HCA Group Leader, Enabling Technologies / AD-HTS, Schering AG

2:30-3:00 Improving Performance of High-Content Assays by Using Division-Arrested Cell Reagents
Dr. Zhong Zhong, Vice President, Drug Discovery Technologies, Cell & Molecular Technologies, Inc.

3:00-3:30 Refreshment Break

3:30-4:00 Advances in Live-Cell imaging: New Tools for Kinetic Analysis
Dr. Robert Graves, Senior Scientist, GE Healthcare

4:00-4:30 Novel Multifunctional Reporter Protein for High-Content Cell Analysis
Dr. Georgyi V. Los, Senior Scientist, Imaging Group Leader, Promega Corporation

4:30 Close of Conference

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