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| EFFICIENCIES DRIVING HTOS |
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Success by Design
Rick Roberts, Ph.D., Senior Medicinal Chemist, Almirall Prodesfarma
A Parallel Synthesis Friendly Approach to Highly Complex Chemical Structures- Post Modifications on Multi-Component Reactions
Irini Zanze, Ph.D., Group Leader, R4CP, Abbott Laboratories
Efficiency-Driven Process for the Parallel Synthesis of Drug-like Molecules
Eduard Felder, Ph.D., Director, Chemical Core Technologies, Nerviano Medical Sciences
TBA
Daryl R. Sauer, Ph.D., Senior Group Leader, High-Throughput Organic Synthesis, Global Pharmaceutical Research and Development, Abbott Laboratories
Centralized Rapid Analog Library Synthesis: Challenges and Strategies
David Nirschl, Ph.D., Research Group Leader, Synthesis & Analysis Technology Team, Pharmaceutical Research Institute, Bristol-Myers Squibb Company
A Flexible Response Library Production Approach
Christoph Huwe, Ph.D., Senior Scientist, Schering AG
Facilitating the Design & Enumeration of Focused Compound Libraries for Virtual Reagent Scanning
Bradley P. Feuston, Ph.D., Senior Research Fellow, Medicinal Chemistry, Merck Research Labs
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| DIVERSIFYING THE TECHNOLOGY |
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Greener Chemical Syntheses via Mechano-Chemical Mixing or Using Microwave Irradiation in Eco-Friendly Media
Rajender S. Varma, Ph.D., U. S. Environmental Protection Agency, National Risk Management Research Laboratory, Sustainable Technology Division
Developing Technologies for Reaction Discovery
John Goodell, Ph.D., CMLD-BU, Post Doctoral Scientist, Center for Chemical Methodology and Library Development (CMLD-BU), Department of Chemistry, Boston University
Improvements in the Synthesis and Purification of Small Molecule Libraries- MAOS and Reagents/Scavengers on Solid Support
Stefan Werner, Ph.D. Research Assistant Professor, University of Pittsburgh Center for Chemical Methodologies & Library Development (UPCMLD), Associate Director, University of Pittsburgh
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| RESOLVING INEFFICIENCIES |
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Research Bottlenecks in Small Biotech: Synthesis versus Purification
Guillermo A. Morales, Ph.D., Senior Scientist, Chemistry, Telik, Inc.
High-Throughput Purification of HTOS Libraries & Cores: Accommodating Changing Needs in HTP
Jill Hochlowski, Ph.D., Senior Group Leader & Research Fellow, Head of High Throughput Purification, Medicinal Chemistry Technologies, Abbott Laboratories
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TECHNOLOGY SPOTLIGHT
Rapid Compound Production: Microwave-Assisted Synthesis,
Work-up and Purification
Farah Mavandadi, Ph.D., Product Manager Marketing, Microwave Systems, Biotage
Scientific Advisory Board
Guillermo A. Morales, Ph.D., Senior Scientist, Chemistry, Telik, Inc.
Christoph M. Huwe, Ph.D., Medicinal Chemistry, Corporate Research, Bayer- Schering AG
Daryl R. Sauer, Ph.D., Senior Group Leader, High-Throughput Organic Synthesis, Global Pharmaceutical Research and Development, Abbott Laboratories
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