February 9, 2012
| Bio-IT World > Drug Discovery


Drug Discovery


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Laying the Foundation for Next-Gen Cancer Diagnostics Bio-IT World | This summer, Foundation Medicine will launch what could be described as the next generation of cancer diagnostics. The Cambridge, Mass.-based company, founded by a premier group of cancer researchers and funded by Third Rock Ventures, Kleiner Perkins Caufield & Byers and Google Ventures, will launch a comprehensive next-gen sequencing (NGS) profile screening some about 200 genes known to be clinically relevant and actionable in cancer using routine, formalin-fixed paraffin embedded patient cancer specimens. 

Warp Drive Bio Charts Course for Natural Product Drugs Bio-IT World | While many major pharma companies have been cutting back their research into natural products, Warp Drive Bio, a new start-up out of Third Rock Ventures in Boston, is dedicated to mining the genome of micro-organisms for potent natural product compounds. And in a striking $125-million deal, Warp Drive has teamed with Sanofi to provide ample funding to get operations off the ground and potentially into orbit. 

Remedies for Safer Drugs

Drug Safety New solutions to seek signals, organize data, train interpreters, expedite reporting, and find better biomarkers. By Deborah Borfitz January 10, 2012 | Pharmacovigilance experts have an abundance

What is (Quantitative) Systems Pharmacology?

By John Russell January 10, 2012 | The Russell Transcript | Just a few days apart in the middle of October, Harvard Medical School (HMS) announced a broad initiative in systems pharmacology and NIH released a like minded white paper,

The Pharmaceutical Safety Data Problem

By Ernie Bush January 10, 2012 | Bush Doctrine | I doubt most people fully appreciate the size and scope of the pharmaceutical safety informatics space. I consider myself an avowed information systems advocate with decades of pharma R&D experience,

NuMedii’s New Way to ‘De-Risk’ Drug Repositioning Work

Stanford University spin off relies on database to identify new drug uses. By Deborah Borfitz November 15, 2011 | A newly minted biotechnology company is offering to match the molecular genomic activity of previously approved medicines to that of known

Recent Sequencing Plans by the Numbers Xconomy | What do 10,000 people with autism, 50,000 people in some remote islands in the North Atlantic, and 1,000 healthy old folks in southern California have in common?

New iReport Product Quickly Processes 'Omics Data Bio-IT World | Ingenuity Systems has just announced its iReport product for quickly making sense of 'omics data and will offer free, early access to the first 5,000 researchers to sign up by October 31.

Predictive Science Center in Russia

AstraZeneca to contribute to development of bioinformatics and predictive medicine in Russia. By Eugene Gerden September 27, 2011 | AstraZeneca, the world’s seventh largest pharmaceutical company, has announced its plans to establish a predictive science center for bioinformatics and predictive

Reevaluating the Role of the Research Librarian

By Rya Ben Shir and Alexander Feng September 27, 2011 | If your image of a research librarian is the soft spoken, bespectacled woman politely shushing you when you’re talking in the library, that outdated perception couldn’t be further from



White Papers & Special Reports

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Managing the Modern Genomics Data Flood
Sponsored by SGI

Managing and storing the perfect storm of multi-disciplined data pouring from next generation sequencers and other omics instruments is a central challenge in life sciences. Discover in this paper how the SGI ArcFiniti storage solution, optimized for unstructured genomics and life sciences data can: 

  • Reduce costs, proactively protect data integrity, and deliver the high performance I/O required for genomics data processing and analysis.  
  • Effectively manage capacities from 156TB to 1.4PB as a disk based, integrated hardware and software platform 


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Turning Genomics Data into Practical Insight
Sponsored by SGI

With worldwide sequencing capacity approaching 13 quadrillion DNA bases annually turning genomics data into knowledge is a true computational challenge. Read this paper and learn how the SGI UV coherent shared memory platform can:  

  • Speed results time while cost competitively tackling the most difficult computational problems across all omics disciplines. 
  • Push performance by scaling to extraordinary levels, up to 256 sockets (2,560 cores, 4,096 threads) per single system (one OS image). 

Provide support for up to 16TB of coherent shared memory in a single system image enabling extreme efficiency across a wide range of compute demands. 



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New Complimentary Market Survey…
Collaborations and Communications Within Drug Discovery Research
Sponsored by Accelrys
This survey was conducted by the Cambridge Healthtech Media Group in January, 2012. It was sponsored by Accelrys related to their HEOS initiative to gather valid information around externalizing collaborative research while improving communications in the cloud. With 310 qualified industry respondents the survey findings reveal useful usage and trends patterns.  An insightful follow-on discussion and webinar related to this survey, and the HEOS by Scynexis SaaS portal is also available on the Bio-IT World website for complementary viewing.
 


Job Openings

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Scientific Software Engineer
Boston MA
$70,000 to $95,000
 
Apply at http://jobs.tessella.com   

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Early Access Collaborations ManagersClick here to find out more and apply   

Oxford Nanopore's GridION technology, VP, Sales and Marketing Click to  Apply  




For reprints and/or copyright permission, please contact  Tim McLucas, (781) 972-1342, tmclucas@healthtech.com .