Cambridge Healthtech Institute’s 7th Annual
Optimizing Cell Line Development
August 6-7, 2015
Part of CHI's 7th Annual The Bioprocessing Summit
August 3-7, 2015 | Westin Copley Place Hotel | Boston, Massachusetts
The “Optimizing Cell Line Development” meeting features experts sharing their case studies and anecdotes that illustrate the strategies they use to reach enhanced expression and lower costs. Their research and experiences provide meaningful insights into how to best select cell lines and hosts, and develop high-producers into late-stage production. Gaining a greater understanding of cells through sequencing and the omics sciences will also be addressed, including the CHO genome research, metabolomics, assays, and QPCR. In addition, challenges for introducing new technologies will be discussed, along with an overview of industrial trends and regulatory perspectives.
Upstream Process Optimization, Automation and Collaboration: An Accelerated Path to the Clinic
Pamela Pegman, Ph.D., Senior Principal Scientist, Pfizer, Inc.
Enabling Evaluation of Polysaccharide Size and Content for DOE Studies in Early Process Phases
Erwin Swennen, Ph.D., Manager, Cell Line and Process Analytics, Bacterial Drug Substance Development, Novartis Vaccines
Developing Cell Lines for Bispecific Antibodies
Martin Bertschinger, Ph.D., Team Leader, Cell Line & Early Process Development, Glenmark Pharmaceuticals
Improving Stability through Vector Design
Thomas Jostock, Ph.D., New Technologies Network Leader / Novartis Leading Scientist, Novartis
Utilizing High Throughput Bioanalytics for Early Detection of Product Impurities
Christina Alves, Ph.D., Scientist, Biogen Idec, Inc.
High-Throughput Analytical Tools Used for Cell Line Development
Shashi Prajapati, Ph.D., Senior Scientist, High-Throughput Analytical Group, Cell Culture Development, Biogen Idec, Inc.
Develop Systems Biology Models Based on Whole-Genome Sequencing of CHO to Guide Cell Line Engineering
Nathan Lewis, Ph.D., Assistant Professor, Systems Biology Research Group, University of California, San Diego
Engineering the Baculovirus Genome for Better Protein Production from Insect Cells
Dominic Esposito, Ph.D., Director, Protein Expression Laboratory, Frederick National Lab for Cancer Research
Optimizing Insect Cell Lines for Production of Structurally Uniform Glycoproteins
Donald Jarvis, Ph.D., Professor, Molecular Biology, University of Wyoming
Screening of Mammalian Cell Clones by Mass Balance of Amino Acids
Wen Wang, Ph.D., Postdoctoral Associate of Prof. Daniel I. C. Wang’s group, Chemical Engineering, Massachusetts Institute of Technology (MIT)
Development of Human Cell Systems for Evaluating the Responses of Drugs Directed at Correcting the Function of Cellular Proteins
Dieter Gruenert, Ph.D., Professor, Otolaryngology-Head and Neck Surgery, University of California, San Francisco
For more details on the conference,
Senior Conference Director
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