About the Conference:
Biology is not static – neither are the tools and technologies that support genomic discovery for basic and pharmaceutical research. Gene expression profiling is preferred, providing common language for finding relationships between health and disease; genetic changes as a result of therapy; markers for toxicology and drug safety; and even potentially leading to personalized medicine. Additionally, it may be possible to capture these revealing expression profiles with as few as a thousand transcripts. Learn from seasoned and savvy researchers who share their experiences using the latest genomic technologies for piecing together the biological puzzle of health and disease at Cambridge Healthtech Institute’s Fifth Annual Advances in Gene Expression Profiling: Technologies. . . Transcripts . . . Therapies.

Session Topics Include:

• Profiling Gene Expression from Tissue
• FFPE Clinical Samples
• Unfixed Frozen Tissue Samples
• Purification of Genomic DNA from Blood
• Technologies. . .Transcripts. . .Therapies
• Non-Coding RNA’s
• Toxic Profiles of Compounds
• Bacterial Pathogen Infection
• Gene Knockdown Models

Presentation Titles and Distinguished Speakers Included on the DVD:

Tackling Technical Barriers to Achieve High Fidelity Gene Expression Data from Formalin-Fixed Paraffin-Embedded Clinical Tissues

Jun Luo, Ph.D., Assistant Professor, Department of Urology, Johns Hopkins Hospital

Comparison of Quantity, Quality, and Microarray Performance of RNA Extracted from Formalin-Fixed Paraffin-Embedded and Unfixed Frozen Tissue Samples

Marshall S. Scicchitano, M.S., Manager, Molecular Pathology, Department of Safety Assessment, GlaxoSmithKline

Walk-Away Purification of Genomic DNA from Large Volume Blood Samples

Eric Vincent, Ph.D., Product Manager - Nucleic Acid Purification, Promega

New Approaches Towards Characterizing Non-Coding RNA’s and Their Role in Health and Disease

Allen Nicholson, Ph.D., Professor, Biology and Chemistry, Temple University

Application of Gene Expression Profiling in Discovery and Early Development to Identify and Characterize the Toxic Profiles of Compounds

Wayne Buck, Ph.D., Cellular Molecular & Exploratory Toxicology, Abbott Laboratories

Genetic Tools to Study Gene Expression During Bacterial Pathogen Infection

Jay Zhu, Ph.D., Assistant Professor, Microbiology, University of Pennsylvania School of Medicine

Novel Gene Knockdown Models for Studying Reprogramming in the Early Embryo

Mylene W. M. Yao, M.D., Assistant Professor, Department of Obstetrics and Gynecology, Stanford University School of Medicine