2nd Annual

Epigenetic Inhibitor Discovery

Chemically Modulating Gene Expression

April 21-22, 2015 


Great opportunity to share and discuss cutting-edge approaches/aspects in drug discovery.

Fabrizio G., Principal Scientist, AstraZeneca

Epigenetic drug discovery is one of the fastest growing and potentially groundbreaking target spaces for developers. Over the past few years, a significant increase in small molecule inhibitors chemically modulating enzymatic activity of Histone Methyltransferases (HMTs), Histone Demethylases (HDMs), and disrupting interactions of the BET family bromodomains have rapidly translated into clinical investigation. Now, with apparent safety and efficacy being demonstrated in clinical trials, the opportunity to develop novel chemical tools and inhibitors against the wealth of epigenetic modifiers is ever present.

Cambridge Healthtech Institute will once again convene leaders in Epigenetic Inhibitor Discovery to bring forth novel and emerging strategies for inhibition, new bioactive tools and inhibitors, and well as strategies for lead optimization to obtain clinically-relevant small molecules. Join fellow drug discovery scientists for this day-and-a-half meeting that is in the first half of our larger Drug Discovery Chemistry event.

Topics may include, but are not limited to: 

  • High-Throughput Screening
  • Virtual Screening
  • Structure and Fragment-Based Design
  • Disrupting Protein-Protein Interactions
  • Biochemical and Biophysical Assays
  • Phenotypic Screening
  • Chemical Biology
  • Lead Optimization
  • Allosteric Modulators

If you would like to submit a proposal to give a presentation at this meeting, please click here.

The deadline for submission is September 29, 2014 

All proposals are subject to review by the Scientific Advisory Committee to ensure the highest quality of the conference program.  Please note that due to limited speaking slots, preference is given to pharmaceutical and biotech companies, regulators and those from academia. Additionally, vendors/consultants who provide products and services to these biopharmaceutical companies are offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships. 

For more details on the conference, please contact:
Kip Harry
Conference Producer
Cambridge Healthtech Institute
Phone: (+1) 781-972-5454
Email: kharry@healthtech.com 

For partnering and sponsorship information, please contact:
Carolyn Benton
Business Development Manager
Cambridge Healthtech Institute
Phone: (+1) 781-972-5412
Email: cbenton@healthtech.com