Property-Based Drug Design in Medicinal Chemistry Track Heaer

As the need for newer and more effective drugs evolves, so do the tools and techniques for drug discovery. Property-based drug design allows researchers and chemists to design drug candidates with the right balance of physiochemical (ADME profiles) and biophysical properties. The fifth annual Property-Based Drug Design in Medicinal Chemistry conference will focus on experimental and in silico approaches to best determine, exploit, and optimize physical properties in order to enhance efficacy, optimize ADME, and reduce toxicity. Conventional small molecules, macrocycles, and protein-protein targets will be addressed. The conference will bring together academic and industry experts to discuss advances in new and evolving technologies and methods, such as data-driven and computational design, molecular metrics, data management, and analysis.

Who should attend: Medicinal chemists, drug discovery scientists, computational chemists, scientists in lead optimization and ADME/DMPK groups.

Topics will include, but are not limited to:

  • Designing macrocycles: Challenges in achieving the right properties
  • Property-based design considerations for protein-protein interaction targets
  • Manipulating physical properties to avoid toxicity
  • in silico drug design techniques, methods, and examples, such as matched molecular pair analysis
  • Structure and ligand-based design
  • Property-based design outside conventional drug space and beyond Lipinski’s Rule of 5
  • Measurement of solubility, permeability and plasma protein binding

If you would like to submit a proposal to give a presentation at this meeting, please click here.

The deadline for submission is November 9, 2015.

All proposals are subject to review by the Scientific Advisory Committee to ensure the highest quality of the conference program. Please note that due to limited speaking slots, preference is given to pharmaceutical and biotech companies, regulators and those from academia. Additionally, vendors/consultants who provide products and services to these biopharmaceutical companies are offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.

For questions or suggestions about the meeting, please contact:
Kaitlin Searfoss
Associate Conference Producer
Cambridge Healthtech Institute
T: (+1) 781-972-5498

For sponsorship and exhibit sales information including sponsored podium presentations, contact:
Joseph Vacca
Associate Director, Business Development
Cambridge Healthtech Institute
T: (+1) 781-972-5431




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