January 18-22, 2016 | Town and Country Resort Hotel | SAN DIEGO, CA 
January 18-22, 2016 | Town and Country Resort Hotel | SAN DIEGO, CA 

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Cambridge Healthtech Institute’s 8th Annual
Protein Purification and Recovery
Streamlining Processes with Innovative Technologies
January 19-20, 2016


Protein purification is the most costly and time-consuming process in the manufacturing of proteins. Challenges are multiplied when purifying complex molecules, such as membrane proteins, bispecifics and antibody-drug conjugates. The Protein Purification and Recovery conference explores how experts are optimizing processes to achieve pure protein while curtailing cost and time. Along with innovating “traditional” technologies such as Protein A and chromatography, leaders also address alternatives and breakthroughs, such as continuous processing. This leading purification meeting includes a highlighted session focused on purifying membrane proteins, and addresses optimizing processes to ensure purity and quality.

Preliminary Agenda 


MEMBRANE PROTEINS


KEYNOTE PRESENTATION
SIMPLEx: Making Water-Soluble Integral Membrane Proteins in vivo Using an Amphipathic Protein Fusion Strategy

Matthew P. DeLisa, Ph.D., William L. Lewis Professor, Chemical & Biomolecular Engineering, Cornell University


FEATURED PRESENTATION
Expression and Sample Preparation of Membrane Proteins for Structure Determination by NMR

Stanley Opella, Ph.D., Professor, Chemistry and Biochemistry, University of California, San Diego


Strategies for High Yield Affinity Purification of Functional G Protein Coupled Receptor from Detergent Solutions

Alexei Yeliseev, Ph.D., Staff Scientist, LMBB, NIH/NIAAA


PURIFICATION STRATEGIES

Purification of Secretory IgA from Lemna minor (Duckweed)

Daniëlle van Wijk, Ph.D., Lead Scientist / Project Leader, Down Stream Processing, Synthon B.V.


PURIFYING ANTIBODIES

Purification Challenges for High-Concentration Monoclonal Antibodies

Hong Li, Ph.D., Principal Scientist, Purification Process Development, Merck

Purification of Common-Light-Chain Bispecific Antibodies

Juergen Nett, Ph.D., Associate Director, High Throughput Expression, Adimab LLC

Developing a Purification Platform for FAB

Jiansheng Wu, Ph.D., Senior Scientist, Protein Chemistry, Genentech, Inc.


STREAMLINING PURIFICATION PROCESSES

Crystallization as a Tool for Scalable, Efficient Purification Techniques in Early Process Step for Purifying Recombinant Proteins

Partha Hazra, Ph.D., Chief Scientific Manager, Research, Biocon

pH-Dependent Sharkbodies for Affinity Purification of Biologics

Harald Kolmar, Ph.D., Professor and Head, Applied Biochemistry, Chemistry, Technical University of Darmstadt




For questions about the meeting, please contact: 

Mary Ruberry
Senior Conference Director
Cambridge Healthtech Institute
Phone: 781-972-5421
Email: mruberry@healthtech.com 

For partnering & sponsorship information, please contact: 

Companies A-K
Jason Gerardi
Manager, Business Development
Cambridge Healthtech Institute
Phone: 781-972-5452
Fax: 781-972-5470
Email: jgerardi@healthtech.com 

Companies L-Z
Carol Dinerstein
Director, Business Development
Cambridge Healthtech Institute
Phone: 781-972-5471
Fax: 781-972-5470
Email: dinerstein@healthtech.com