Functional Genomics Screening Strategies

Cambridge Healthtech Institute’s 10th annual conference will cover the latest in the use of chemical genomics tools, cDNA overexpression assays and the potential use of micro RNA (miRNA) and long non-coding RNAs for identifying and validating drug targets, exploring unknown cellular pathways, and for performing translational studies such as, biomarker discovery, drug modifier screens and more.

TUESDAY, OCTOBER 2

Exploring Diverse Applications

1:30 pm Chairperson’s Remarks

Christophe Echeverri, Ph.D., CEO & CSO, Cenix BioScience

1:40 Synergistic Application of RNAi Screening, Next-Generation Sequencing and Expression Profiling to Biomarker Discovery

Namjin Chung, Ph.D., Senior Research Investigator, Applied Genomics, Bristol-Myers Squibb Co.

2:10 A Global RNAi Screen Identifies Novel Chemosensitizer and Chemoresistant Oncology Targets Leading to Combination Therapies and Markers of Drug Resistance

Attila Seyhan, Ph.D., Senior Biomarker Discovery and Development Leader, formerly at Translational Immunology, Biotherapeutics Clinical R&D, Pfizer, Inc.

2:40 A Genome-Wide Screen for Novel Genes Involved in Sensitisation to Histone Deacetylase Inhibitors

Kaylene Simpson, Ph.D., Head, Victorian Centre for Functional Genomics, Cancer Genetics, Peter MacCallum Cancer Centre, Australia

3:10 Refreshment Break in the Exhibit Hall with Poster Viewing

3:45 Genomic Platforms to Generate Unbiased Responder and Treatment Hypotheses for Oncology Translational Research

Jing Li, Ph.D., Director of Genomics Screening, Discovery and Pre-clinical Science, Merck Research Laboratories

4:15 Discovery of Cancer Drug Targets Using RNAi Screening with Pooled Lentiviral shRNA Libraries

Paul Diehl, Ph.D., Director, Business Development, Cellecta, Inc.

4:45 Comprehensive Analysis of Host Factors Modulating HIV-1 Replication Using Multiple RNAi Libraries

Abraham Brass, M.D., Ph.D., Assistant Professor, Department of Microbiology and Physiology Systems, University of Massachusetts Medical School

5:15 PANEL DISCUSSION: Need for Standardization in RNAi Screens

Moderator: Christophe Echeverri, Ph.D., CEO & CSO, Cenix BioScience

5:45 End of Day

Day 1 | Day 2 | Download Brochure