Routine and Advanced FTIR Analysis of Protein: Case Studies, Advances, and Applications


May 15, 2013
11:00 am to 12:30 pm EDT

 

Sponsored by
Bruker Optics - ConfoCheck
 


Symposium Course Description: 

The symposium course will describe the most advanced Fourier Transform infrared spectrometer system, the ConfoCheck system, for the study of protein, in particular protein structure. University (Dr. Peter Gross, University of the Saarland) and industry (Dr. Doug Kamen, Regeneron Pharmaceuticals, Inc.) speakers will provide case studies and examples of the utility of the ConfoCheck system in characterizing proteins in demanding environments. In addition, advances in the study of protein degradation and aggregation will be presented.

Attend This Webinar to Understand: 

  • The value of the ConfoCheck system as a tool for studying protein in demanding environments such as the pharmaceutical industry
  • The utility of FTIR spectroscopy in protein characterization and formulation development
  • The utility of FTIR spectroscopy in the study of protein aggregation and degradation

Who Should Attend: 

  • Formulations Division
  • Drug Research and Development Divisions
  • Quality Control Groups
  • Scientists

Program Agenda: 

  • The ConfoCheck SystemCruz Hinojos, Ph.D., Applications Scientist, Bruker Optics 
  • Application of FTIR in Therapeutic Protein DevelopmentDoug Kamen, Ph.D., Staff Scientist, Formulations Development, Regeneron Pharmaceuticals, Inc. 
  • Infrared Spectroscopy for Biopharmaceutical Protein AnalysisPeter Gross, Ph.D., Chief Scientific Officer, Department of Biotech Processes and Analytics, Pharmbiotec GmbH 
  • Q&A Session 

Speaker Information: 

Cruz HinojosCruz Hinojos, Ph.D.
Applications Scientist, Bruker Optics 

 

Bio: I received my Bachelor’s Degree in Biology from Texas Tech University. I earned my doctoral degree in Physiology at the University of Texas-Houston Graduate School of Biomedical Sciences. For my dissertation I researched molecular mechanisms of renal dysfunction in relation to the development and maintenance of hypertension. I performed post-doctoral work at Baylor College of Medicine in the Cell Biology Department. I researched the role of steroid receptors in the development of cancer. For this, I developed high content imaging assays. Currently, I oversee Life Science instruments and applications at Bruker Optics.

Doug Kamen, Ph.D.
Staff Scientist, Formulations Development, Regeneron Pharmaceuticals, Inc. 

Bio: I received my Bachelor’s Degree in Chemistry from Hunter College CUNY. I went on to earn a Ph.D in Biochemistry from Colorado State University. For my dissertation I studies energetic and kinetic mechanisms of protein folding. I subsequently went on for post-doctoral research at Albert Einstein College of Medicine where I used NMR to study the structure of integral membrane proteins. After post-doc I was an Assistant Professor of Chemistry at Adelphi University. I taught chemistry and biochemistry while continuing research on protein folding and stability. Currently I am a Staff Scientist in the Formulations Development Group at Regeneron Pharmaceuticals. Among my expertise are chemical and physical analyses of protein structure including FTIR, CD, fluorescence and NMR spectroscopies.

Peter GrossPeter Gross, Dr.
Chief Scientific Officer, Department of Biotech Processes and Analytics, Pharmbiotec GmbH
 

 


Bio: Dr. Gross received his Ph.D. from Saarland University, then continued onto the Post-Doc position at the Fraunhofer-Institute.  His previous positions include being a Head of Analytics and Method development at Symbiotec GmbH, before becoming a CSO, Department of Biotech Processes and Analytics at Pharmbiotec GmbH.
 

Moderator Information: 

Cruz Hinojos, Ph.D., Applications Scientist, Bruker Optics 



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