Safer Drugs – Save Money: BASF subsidiary Metanomics Health launches MetaMap®Tox – a validated next-generation in vivo tool for early and systemic drug safety testing

November 29, 2012
11:30 am – 12:50 pm EST


Sponsored by
Metanomics Health

Symposium Course Description: The After a brief introduction on the background of the database MetaMap®Tox containing rat plasma metabolome data for more than 500 reference compounds, Niels Möller will summarize the key benefits of MetaMap®Tox application for better and faster assessment of pre-clinical toxicological profiles of NCEs as well as provide some key findings from the successful validation through the Drug Safety Executive Council. Dr. Hennicke Kamp will continue to showcase the typical project design as well as the service packages offered. Finally, data from a case study on Drug Induced Liver Injury (DILI) demonstrating the potential of MetaMap®Tox to detect clinical DILI will be shared.

Learning Objectives:

  • Understand how MetaMap®Tox products can leverage preclinical safety assessment for exploratory and regulatory in vivo toxicology (includes key results from the technical validation by the Drug Safety Executive Council - DSEC)
  • Understand how to integrate MetaMap®Tox project design into routine pharmaceutical toxicology testing as well as MetaMap®Tox service packages offered
  • Case Study for Drug Induced Liver Injury (DILI): Understand the value of MetaMap®Tox for aiding in the preclinical assessment of candidate pharmaceuticals for their potential to elicit drug-induced liver injury in clinical trial or practice

Who Should Attend:

Managers, Scientists, Directors, Heads of , Vice President, SVP, President of:

  • Toxicology
  • Non – Clinical Drug Safety / Pre-clinical Drug Safety
  • Drug Safety
  • Investigational Toxicology
  • Molecular Toxicology
  • Regulatory & Exploratory in vivo Toxicology

Program Agenda:

  • MetaMap®Tox background
  • Key benefits/utility for pre-clinical in-vivo decision making (incl. key results from the validation by DSEC)
  • MetaMap®Tox project design & MetaMap®Tox service packages
  • Case Study Drug Induced Liver Injury (DILI)

Speaker Information: 

Niels MöllerM
MBA, Managing Director, Metanomics Health – a BASF Group Company
Tegeler Weg 33
10589 Berlin

Dr. Hennicke Kamp
Head of Services Experimental Toxicology and Ecology, BASF SE
Carl-Bosch-Strasse 38
67056 Ludwigshafen

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