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Optimizing Mammalian Cell Lines


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Overview
Gene expression in mammalian cells is the foundation for protein production. As more protein-based products head into development, the need to refine processes for optimizing cell line development increases. Reducing the time needed to identify high-expressing clones and develop cell lines is essential for trimming a project’s overall costs.


The “Optimizing Mammalian Cell Lines” meeting features experts sharing their protocols and case studies illustrating how they have optimized cell lines to reach enhanced expression. Their insights and experiences will provide real-world details to help you conquer the challenges of cell line development. As you seek to enhance your skills and knowledge, make time to join the information exchange and networking with colleagues from around the world who share common cellular goals on the path to protein production.

Preliminary Topics:


  • Cell line selection & optimization
  • Clone selection & optimization
  • Gene delivery into cells
  • Vector design & engineering
  • Monitoring gene expression
  • Metabolic engineering of cells
  • Transfection
  • Electroporation
  • Phosphorylation
  • Growth properties
  • Promoter activity
  • Reporter genes
  • Signaling pathways
  • Stability
  • Screening
  • Process development & optimization
  • Protocols & Case Studies

If you would like to give an oral presentation in this conference, please submit a proposal including a title and brief summary about your recent work in the area of Optimizing Mammalian Cell Lines. All proposals are subject to review by the Scientific Advisory Committee to ensure the highest quality of conference programming.

To submit a proposal for consideration please click here

Deadline for submission is February 19, 2010.


For more information, please contact:
Mary Ruberry
Conference Director
Cambridge Healthtech Institute
Phone: 781-972-5421
Email: mruberry@healthtech.com 

For sponsorship information, please contact:
Suzanne Carroll
Manager, Business Development
Cambridge Healthtech Institute
Phone: 781-972-5452
Email: scarroll@healthtech.com

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