January 18-22, 2016 | Town and Country Resort Hotel | SAN DIEGO, CA 
January 18-22, 2016 | Town and Country Resort Hotel | SAN DIEGO, CA 

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Cambridge Healthtech Institute’s 2nd Annual
Membrane Proteins
A Valuable Resource and Target
January 19-20, 2016


Membrane proteins are the gateways to the cell and are valuable drug targets. For researchers to design better-targeted drugs, they need to know their structure and functional characteristics. Cambridge Healthtech Institute’s 2nd Annual Membrane Proteins conference addresses the strategies and solutions for their extraction, expression and purification, and features case studies showcasing their value as a drug target. Join the in-depth exploration of how to obtain functional membrane proteins, and learn more about this important protein class.

Preliminary Agenda 


PURIFICATION


KEYNOTE PRESENTATION
SIMPLEx: Making Water-Soluble Integral Membrane Proteins in vivo Using an Amphipathic Protein Fusion Strategy

Matthew P. DeLisa, Ph.D., William L. Lewis Professor, Chemical & Biomolecular Engineering, Cornell University


FEATURED PRESENTATION
Expression and Sample Preparation of Membrane Proteins for Structure Determination by NMR

Stanley Opella, Ph.D., Professor, Chemistry and Biochemistry, University of California, San Diego


Strategies for High Yield Affinity Purification of Functional G Protein Coupled Receptor from Detergent Solutions

Alexei Yeliseev, Ph.D., Staff Scientist, LMBB, NIH/NIAAA


DIFFICULT-TO-EXPRESS PROTEINS

Light-Controlled Intracellular Delivery of Native Peptides and Proteins

Norbert O. Reich, Ph.D., Professor, Chemistry & Biochemistry, University of California, Santa Barbara

Cell-Free Expression of High-Quality GPCRs in Eukaryotic and Prokaryotic Lysates

Ralf-Bernhardt Rues, Research Fellow, Institute of Biophysical Chemistry, Goethe University Frankfurt

Membrane Proteins: From Lab-Scale toward Large-Scale Production

Julie Bomholt, Ph.D., Protein Specialist, Research and Development, Aquaporin A/S

Expression of Membrane Recombinant Hemagglutinins, Components of Influenza Vaccine Flublok®, Using Baculovirus Expression System

Nikolai Khramtsov, Ph.D., Associate Director, Upstream Development, Process Development, Protein Sciences Corp.


DISCOVERY AND DEVELOPMENT OF ANTIBODY TARGETS

Antibody Discovery against GPCRs Using Yeast Antibody Display Technology

Abhishek Datta, Ph.D., Scientist II, Drug Discovery, Biogen

Engineering Ion Channels for Structural Studies and Ligand Discovery

Susmith Mukund, Senior Research Associate, Genentech, Inc.

Antibody-Mediated Blockade of Human Orai1 Inhibits T Cell Activation in vitro and in vivo 

Stefan Zahn, Ph.D., Principal Scientist, Antibody Technology, Novo Nordisk A/S

Targeting Tumor-Specific Cell Surface Antigens

Madan Katragadda, Ph.D., Senior Principal Scientist, Pfizer

Challenges in Generating Antibodies to Integral Membrane Proteins

Ramkrishna (Ramu) Sadhukhan, Senior Group Leader, AbbVie Bioresearch Center




For questions about the meeting, please contact:  

Mary Ann Brown
Executive Director, Conferences
Cambridge Healthtech Institute
Phone: 781-972-5497
Email: mabrown@healthtech.com  

For partnering & sponsorship information, please contact:  

Companies A-K
Jason Gerardi
Manager, Business Development
Cambridge Healthtech Institute
Phone: 781-972-5452
Fax: 781-972-5470
Email: jgerardi@healthtech.com  

Companies L-Z
Carol Dinerstein
Director, Business Development
Cambridge Healthtech Institute
Phone: 781-972-5471
Fax: 781-972-5470
Email: dinerstein@healthtech.com