2013 Archived Content
Fifth Annual

Integrated R&D Informatics and Knowledge Management

Leveraging IT and Informatics to Enable Global Information Sharing


Day 1 | Day 2 | Day 3 

Thursday, February 14

7:00 am Breakfast Presentation (Sponsorship Opportunity Available) or Morning Coffee

8:00 - 9:40 Plenary Keynote Panel: Emerging Technologies & Industry PerspectivesThis session features a series of presentations on emerging and hot technologies in diagnostics, drug discovery & development, informatics, and oncology. Interactive Q&A discussion with the audience will be included. - Read more 

Sponsored by



Biocartis  Elsevier  Luminex  RemedyMD  Scientia Advisors  Singulex 


9:40 Refreshment Break in the Exhibit Hall with Poster Viewing


Leveraging Information Across Multiple Internal Sources 

10:40 Chairperson's Remarks

Chris L. Waller, Ph.D., Director, Cheminformatics, Discovery Merck Research Labs

10:45 Breaking Down Information Silos

Chris L. Waller, Ph.D., Director, Cheminformatics, Discovery Merck Research Labs

Much has been written about the various technologies that can be utilized to empower translational informatics systems. This talk will focus on behavioral barriers that impede the implementation of translational systems in support of the emerging open research and development environment.

11:15 The Path to Linked Data in BioPharma

Tom Plasterer, Ph.D., Principal Informatics Scientist, Semantic Framework Lead, AstraZeneca

As BioPharma adapts to incorporate nimble networks of suppliers, collaborators, and regulators the ability to link data is critical for dynamic interoperability. Adoption of linked data paradigm allows BioPharma to focus on core business: delivering valuable therapeutics in a timely manner.

11:45 Towards a Data-Driven Framework for Life Sciences Integration

Paul Konstant, Manager Informatics, Janssen Pharmaceuticals

Interdisciplinary integration of experimental outcomes continues to face a changing landscape of scientific and technology methods. In this work, we present the Independent Variable Framework designed to manage diversity and change. The framework supports capturing outcomes in their complete context, a critical factor in assuring appropriate interpretation and integration.

Elsevier 12:15pm Luncheon Presentation I: Repurposing Scientific Discovery - Delivering Structured Intelligence from Unstructured TextKevin Bobofchak, Ph.D., Pathway Studio Product Manager, ElsevierPathway Studio┬« is a powerful analytical platform that includes the most comprehensive knowledgebase of molecular findings that are accurately extracted from scientific publications by MedScan┬«.   In the context of these facts, users can analyze their gene expression, GWAS and NGS datasets using the robust toolset, thus enabling validation of new interactions and obtaining insights into biological mechanisms.

ACD Labs New12:45 Luncheon Presentation II: Breathing Life into Your Analytical Data Ryan Sasaki, Director, Global Strategy, ACD/LabsAnalytical data from different departments can be spread across different information silos throughout an organization. Despite significant investments in data acquisition and storage, the knowledge and decision-making associated with this data is rarely retained. Bringing this data to life requires systems that can handle all data types and vendor formats as well as a means to extract the information from data as it relates to chemical structure(s).  1:15 Refreshment Break in the Exhibit Hall with Poster Viewing  

1:40 Chairperson's Remarks

Barry Bunin, Ph.D. CEO, Collaborative Drug Discovery (CDD, Inc.)

1:45 Leveraging Information to Drive Drug Discovery: Lessons Learned Over 25 Years

Mic Lajiness, Ph.D., Research Advisor, Eli Lilly

It has long been a desire in the pharmaceutical industry to have an integrated Cheminformatics System that provides scientists the ability to access and exploit corporate research data to facilitate the discovery and development of new therapeutic agents. In the face of this desire, it is quite surprising that there are startlingly few examples of commercial or proprietary solutions that are well regarded, have stood the test of time, and are considered to be successful. Some of the most notable exceptions in this bleak landscape are Cousin, Chemlink, and Mobius. These (were) are production systems that started in 1981 (Cousin) with one continuing today (Mobius). This presentation will highlight many of the lessons learned in the past 30+ year that have led to these successful developments. These lessons will encompass technical, philosophical, social, and marketing aspects to the development of successful solutions in this application area and also some of the pitfalls that ultimately lead to failure.

2:15 Registration and Management of Non-Sequenced Based Biological Samples

Christina Lu, Manager, IT, Novartis Pharmaceuticals Corp.

2:45 Applying Lessons Learned from Life Science to Downstream Energy Informatics

Len Koenig, Senior Research Associate Research Computing, Computer Science and Chemistry, ExxonMobil Research and Engineering

As Life Sciences and Downstream Energy face similar challenges of managing research data, we implemented common practices to merge and precondition disparate or complex data. We will describe the benefits of these activities and extend lessons learned and best practices across our mutual industries.

ParthysReverseInformatics3:15 World's Disclosed Knowledge in Digestible Format: Externalization and Reverse Informatics

Srinivasan Parthiban, Ph.D., CEO & President, Parthys Reverse InformaticsThis talk will discuss the concept of Reverse Informatics and speaker's experience in externalization of scientific information needs, its current trends & best practices. Data capture and curation in Biomarkers, Oncology and Medicinal Chemistry research will also be discussed.

IDBS 3:30 Perspectives on Collaboration Models Across the Health Science Ecosystem Paul Denny-Gouldson, Ph.D., Vice President, Translational Medicine, IDBSPharmaceutical companies are moving from centralised organisations to virtual network of internal labs, CROs, academic partners and government agencies. Data is central to these collaborative ecosystems and needs to be consistently captured, integrated, managed, tracked and analysed. This presentation will highlight key case studies to demonstrate how companies can gain competitive advantage from their increasingly complex network of data and partners.

3:45 Valentine's Day Celebration and Poster Competition Winner Announced in the Exhibit Hall (Last Chance to View Posters)


Platforms to Enable Internal and
External Collaboration and Drive Discovery

4:30 Chairperson's Remarks

Mary Bradley, Ph.D., MBA, CollaborationFinder

4:35 Leveraging the Google Apps Enterprise Platform to Enable Internal and External Collaboration at the Broad Institute

Lukas Karlsson, Lead Architect, IT & Head, Collaboration & Content Management, Broad Institute

The Broad Institute of MIT & Harvard is a partnership between researchers at the Broad and many researchers across the Harvard & MIT campus and partner hospitals across Boston. The Broad Institute also has a number of collaborations that span the globe. The Broad Information Technology Services Group has made a significant investment in the Google Enterprise platform to enable collaboration across our organization. In the presentation you will learn how we have leveraged the Google Apps Enterprise Platform to facilitate collaboration, challenges we have faced and how we complement other collaboration tools to provide a rich collaboration experience.

Collaborative Drug Discovery - small logo5:05 A More Economical, Collaborative Business Model for Drug Discovery: The Collaborative Drug Discovery Paradigm

Barry Bunin, Ph.D., CEO, Collaborative Drug Discovery (CDD, Inc.)

Cloud computing and leveraging the Internet for secure collaborations are becoming more important.  A more economical, collaborative business model for drug discovery has emerged. Representative commercial and neglected disease NIH, BMGF, industry, and academic case studies will be shared.

5:35 A Roadmap to Successful Collaborations: Lessons from Past and Present

Mary Bradley, Ph.D., MBA, CollaborationFinder

Collaboration is widely viewed as a necessity to improve productivity and increase innovation. Identifying factors and behaviors that contributed to successful collaborations, as well as cultural factors that can impede success, provide insight into what drives the best collaborative outcomes.

6:05 Sponsored Presentations (Opportunities Available)

6:35 Close of Day

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Premier Sponsors

Beckman Coulter Life Sciences 

Boston Healthcare



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Cofactor Genonics


Menarini Silicon Biosystems






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