2014 Archived Content

Cambridge Healthtech Institute’s Second Annual

Digital Pathology

Transforming Medicine in a Digital World

February 10-12, 2014 | Moscone North Convention Center | San Francisco, CA


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Wednesday, February 12

7:00 am Breakfast Presentation (Sponsorship Opportunity Available) or Morning Coffee

8:00 Plenary Keynote Session (Click Here For More Details)  

9:45 Refreshment Break and Poster Competition Winner Announced in the Exhibit Hall


10:35 Chairperson’s Remarks

Anil Parwani, M.D., Ph.D., Director, Pathology Informatics, Pathology, University of Pittsburgh Medical Center

10:40 Management of Clinical Digital Image Files

John H. Sinard, M.D., Ph.D., Professor, Pathology; Director, Pathology & Informatics; Associate Director, Anatomic Pathology, Yale University

Pathology departments accumulate digital image files of all different kinds. Proper management of these files is important to assure their availability. Appropriate consideration needs to be given to the design of the image storage process since the initial solution chosen is likely to persist for years. This talk will discuss many of the issues that need to be considered in designing a clinical digital image management solution.

11:10 Implementing WSI in a Large Academic Hospital

Thomas W. Bauer, M.D., Ph.D., Medical Director, ePathology, Cleveland Clinic

Successful implementation of WSI for research, education, and patient care in a large academic department requires acceptance among more than just early adopters. This talk will review our strategy to develop, implement and measure a dynamic “digital education library,” and the outcome of the secondary diagnosis validation study.

11:40 Image Analysis Algorithms: What Can They Do for Pathology?

Metin N. Gurcan, Ph.D., Associate Professor, Biomedical Informatics, Ohio State University

The qualitative analysis of histopathological images is a time-consuming process and is subject to inter- and intra-reader variations. This often negatively affects the diagnosis, prognosis and treatment of patients. In this talk, we will discuss how computer-assisted interpretation of histopathological slides can assist pathologists in their decision-making.

12:10 pm Session Break

12:20 Luncheon Presentation (Sponsorship Opportunity Available) or Lunch on Your Own

1:00 Refreshment Break in the Exhibit Hall and Last Chance for Poster Viewing


1:40 Chairperson’s Remarks

Liron Pantanowitz, M.D., Associate Professor, Pathology, University of Pittsburgh Medical Center; Pathology, UPMC Shadyside

1:45 Use of Whole Slide Imaging for Primary Diagnosis in Canada

Andrew J. Evans, M.D., Ph.D., FRCPC, Staff Pathologist & Associate Professor, University Health Network, Laboratory Medicine Program

There is growing acceptance for using WSI for diagnostic purposes, including consultations and frozen sections. Interest in Canada and other countries is also building around the use of this technology for primary diagnosis, particularly in multi-site institutions with consolidated pathology departments and subspecialty sign out. This presentation will review logistical, regulatory and medicolegal factors that facilitate the use of WSI for primary diagnosis in these situations in Canada.

2:15 Digital Imaging of Peripheral Blood Smears: Challenges and Opportunities

Christopher Naugler, M.D., BScH, MSc, CCFP, FCFP, FRCPC, Assistant Professor, Pathology and Laboratory Medicine, University of Calgary, Division Head, General Pathology, Calgary Laboratory Services

Digital imaging of peripheral blood smears, combined with image analysis software is becoming commonplace in clinical laboratories. The single cell nature of blood image analysis is analogous to cytologic image analysis but still has room for improvement in accuracy. New algorithms (especially when applied in parallel) may improve image analysis accuracy.

2:45 Implementation of WSI for Consensus Review in Clinical Trials

Stephen M. Hewitt, M.D., Ph.D., Clinical Investigator, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute

The implementation of WSI in a clinical trial setting offers a critical view of the challenges in implementation of the technology into the pathology routine. This presentation will discuss the advantages of the adoption of WSI in a clinical trial, as well as the considerations and technical task of implementation for a successful integration of digital pathology in clinical trials.

3:15 How Molecular Pathology Blends with Laboratory Medicine

George D. Lundberg, M.D., Chief Medical Officer & Editor in Chief, CollabRx

3:45 Refreshment Break


4:00 Chairperson’s Remarks

Anil Parwani, M.D., Ph.D., Director, Pathology Informatics, Pathology, University of Pittsburgh Medical Center

4:05 Why Investing in Digital Imaging is a Good Bet

Anil Parwani, M.D., Ph.D., Director, Pathology Informatics, Pathology, University of Pittsburgh Medical Center

As pathology practices consider if they should invest in digital pathology or not, they will encounter difficult decisions surrounding the cost of the technology vs. the benefits. This lecture will provide an overview of some clinical applications of digital pathology and the types of uses of this technology that would be potentially beneficial to the practices in spite of the high costs of the technology.

4:35 Alterations in Nanoscale Nuclear Architecture for Cancer Diagnosis and Prognosis

Yang Liu, Ph.D., Assistant Professor, Medicine, Bioengineering, Hillman Cancer Center, University of Pittsburgh

Alteration in nuclear architecture is one of the hallmarks in cancer diagnosis and prognosis, but the diffraction-limited resolution of conventional light microscopy limits their accuracy in some scenarios of cancer diagnosis and prognosis. Our group developed a novel optical microscopy system to interrogate 3D nanoscale alterations in nuclear architecture using clinically prepared routine tissues and cells. We will present their use to improve cancer diagnosis and prognosis in multiple cancers.

5:05 Whole Slide Image Analysis in Fine Needle Aspiration Biopsy and Cytopathology

Brian Collins, Ph.D., Associate Professor, Pathology and Immunology, Washington University, St. Louis

Whole slide images (WSI) offer a way to capture fine needle aspiration smears and utilize image analysis tools to objectively evaluate morphologic features. Indeterminate classification of cases presents a challenge in cytopathology. The application of WSI image analysis in cytopathology will be detailed and potential uses discussed.

5:35 Close of Conference Program

MMTC Digital Path gif 

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