Molecular Medicine Tri-conference Plenary Session

Plenary Keynote Introductions


5:00 – 6:00 pm

Plenary Session Introduction:

Brian Wright, Vice President, Sales & Marketing, Paradigm

Integrating the Digital Universe of Data with Consumer-Driven Mobile Apps and Large-Scale Panomics Data to Better Understand, Treat, and Prevent Disease

Andrew KasarskisAndrew Kasarskis, Ph.D., Co-Director, Icahn Institute for Genomics and Multiscale Biology; Vice Chairman, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai

The digital universe of data continues to grow at an exponential pace, now comprising more than 1 zettabyte of useable data. Contributing to this big data revolution are panomic technologies, which have made possible the routine sequencing of whole genomes and transcriptomes, and wearable and implantable sensors that make the acquisition of real-time physiologic data across many dimensions a reality in populations of individuals. With extensive molecular, cellular, and physiologic data generated on individuals in a longitudinal fashion, the potential exists to characterize the health of an individual at a far deeper level than has been possible before. Better characterization of an individual’s health will lead to more precise diagnoses, treatments, and preventative strategies for disease at a highly personalized level. Towards this end, we have developed a predictive, multiscale framework that enables us to understand the health of an individual at the molecular, cellular, organ, organism and community scales so that we can better diagnose, treat, and prevent disease.

Biographical Profile:
Dr. Kasarskis leads collaborative projects aimed at new therapeutics and diagnostics, and his research focuses on developing and applying technology to several areas including pathogen surveillance, pharmacogenomics, and the genetics of sleep. He has over a decade of experience managing research and technology development projects in software engineering, drug development, human and mouse genetics, and other biological research applications. Prior to Mount Sinai, he held positions at Pacific Biosciences, Sage Bionetworks, and Merck. Dr. Kasarskis holds a PhD in Molecular and Cellular Biology from UC Berkeley as well as a BS in Biology and a BA in Chemistry from the University of Kentucky. 


8:00 – 9:00 am

Plenary Session Introduction:

Peter Heseltine, CMO, Singulex, Inc.

The Dawn of a New Research Model: The Case for Parent - Clinician - Researcher Collaboration

Matt WilseyMatt Wilsey, President, Grace Wilsey Foundation

There are over 7,000 known rare diseases that affect an estimated 30 million Americans and 350 million people worldwide. The number of diseases with a known genetic cause is going to increase rapidly with next generation sequencing. Science is not equipped to handle the explosion. Reduced government funding has exacerbated the problem. Science will have trouble understanding and treating these diseases quickly and cost effectively using the historical model. A new approach is needed. One based on parent, clinician, and researcher collaboration. This presentation will propose the “NGLY1 Model”. NGLY1 Deficiency is a complex and devastating neuromuscular disease that affects less than 50 confirmed patients globally. An individual family personally affected by NGLY1 researched, recruited, and assembled a global team of 40 researchers across 10 international centers during the last 18 months. The level of speed and collaboration is unparalleled. The team represents the very best in multiple fields akin to the “Manhattan Project”. This talk will explain how this strategy can be applied to both rare and common diseases for faster, cheaper, and more comprehensive disease understanding and treatment.

Biographical Profile:
Matt is a Silicon Valley angel investor and advisor. His investments include Nimble Storage, Practice Fusion, Pintrest, Virtual Instruments, Bonobos, LYFE Kitchen, Caveman Foods, Frontier Snacks, Juicero, Rinse, Moment, Tout, Pinrose, Interior Define, Gear Launch, and Weddington Way. In addition to consumer products and services, Matt invests in and advocates for biomedical research, drug development, and genetic sequencing technologies. Before moving to the investment side, he spent many years as a front-line operator. Most recently, Matt was Co-Founder and Chief Revenue Officer of CardSpring, a payment infrastructure company that was acquired by Twitter. Previously, Matt ran West coast sales and business development for He was responsible for building Howcast’s instructional content library, distribution network, and strategic relationships. Before Howcast, Matt worked for Kohlberg Kravis Roberts (KKR) on the Capital Markets team focused on new product development, capital raising, and investor relations. Prior to that, Matt spent five years as Co-Founder and Vice President of Business Development at, where he was responsible for all content and distribution deals. He started his career serving in various roles at the White House and the Department of Defense. Matt became a rare disease hunter and advocate after his daughter, Grace, was born with NGLY1 Deficiency. He has since funded over 40 scientists at 10 medical centers in 3 countries with the sole purpose of treating the disease. Matt holds a B.A. from Stanford University and a M.B.A. from Stanford's Graduate School of Business. Matt sits on the Board of Directors of the Grace Wilsey Foundation where he is also President, Global Genes, The Lucile Packard Foundation for Children’s Health, the EveryLife Foundation for Rare Diseases, and Perlstein Lab.


4:10 – 5:00 PM

Join us for this complimentary reception and casually network with other delegates, exhibitors, sponsors, poster presenters, and speakers in an informal, fun setting. Cocktails and light hors d’oeuvres will be served.


8:00 – 9:45 am

Plenary Session Panel: Emerging Technologies and Industry Perspectives


Bernard Andruss, Ph.D., Vice President, CDx Development and Regulatory Affairs, Asuragen, Inc.

Yuling Luo, Ph.D., CEO and Founder, Advanced Cell Diagnostics

Rudi Pauwels, Ph.D., Founder, CEO & Executive Chairman, Biocartis

Michael Powell, Ph.D., CSO, DiaCarta,Inc.

Pawan Singh, Director, Workflow Solutions, Executive Management Leica Biosystems

Joe Beechman, Ph.D., Senior Vice President, R&D, NanoString Technologies

Lynn Zieske, Ph.D., Principal Scientist, Life Science, Singulex, Inc.

Mark Hughes, Senior Product Manager, Systems Biology & Analytics, Thomson Reuters



Michael Roehrl, M.D., Ph.D., Associate Professor of Pathology, University of Toronto

Sponsored by:

Advanced Cell Diagnostics 




Leica Biosystems 



 Thomson Reuters  

Premier Sponsors:   


Jackson Laboratory - small logo  


 Precision for Medicine 


Silicon Biosystems 

Thomson Reuters-Large