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Re-Entering Antibacterial Drug Development Summit



We are designing our Second Annual Re-Entering Antibacterial Drug Development Summit. The Summit was very well received in 2014, and in 2015 it will include three conferences:

  • Antibacterial R&D 
  • Clinical Development and Commercialization of Antibacterials 
  • Diagnostics to Guide Antimicrobial Stewardship and Drug Development 

According to the Centers for Disease Control and Prevention, antibiotic-resistant infections are associated with an additional 23,000 deaths and 2 million illnesses in the United States each year. The estimated annual impact of antibiotic-resistant infections on the national economy is $20 billion in excess direct health care costs, and as much as $35 billion in lost productivity from hospitalizations and sick days. By holding the Re-Entering Antibacterial Drug Development Summit, we at Cambridge Healthtech Institute are trying to contribute to the efforts to revive antibacterial pipeline, and to improve antimicrobial stewardship in the United States and worldwide. This Summit is designed as a forum for knowledge and opinion exchange between the major stakeholders, who are shaping the current state of antibacterial discovery and development. Please see below the lists of the preliminary topics to be discussed at each of the tracks.

Antibacterial R&D (November 16-17) 

  • New targets and platforms  
  • Novel screens  
  • Antibacterial biologics: monoclonal antibodies, peptides, antibody drug conjugates  
  • Addressing gram negatives  
  • Addressing the GAIN pathogens  
  • Mechanisms of resistance  
  • Species-specific therapy development  
  • Broad spectrum vs. selective antibiotics  
  • Combination antibacterial therapy  
  • Pk-PD in support of antibacterial drug development  
  • Targeting persisters

Clinical Development and Commercialization of Antibacterials (November 17-18) 

  • Clinical trials for antibacterial therapeutics  
  • Regulatory challenges  
  • Pricing strategy  
  • New FDA guidelines  
  • New EMA guidelines  
  • How to overcome the low profitability barrier  
  • Prevention vs. treatment paradigms: prolonged antibacterial therapy  
  • Following the global trends in emerging infectious diseases  
  • New business models for antibiotics

Diagnostics to Guide Antimicrobial Stewardship and Drug Development (November 17-18) 

  • Molecular diagnostics to enhance antibiotic stewardship
  • Diagnostics to enable pathogen-specific clinical development
  • Rapid diagnostics and antibiotic susceptibility testing for clinically significant infections
  • NGS-based and PCR-based molecular assays  
  • Rapid nano/microfluidics for diagnosis of bacterial infections  
  • Integrating pathogen, human and microbiome genomics  
  • Point-of-care microbiology  
  • Identifying pathogens in culture negative infections  
  • Co-commercialization of antibiotics and rapid diagnostics/susceptibility assays

Scientists who wish to give a podium presentation are encouraged to submit a proposal based on their work in the area of antibacterial drug development. Please remember to specify the conference you are interested in and to provide your full contact information.

All proposals are subject to review by the Scientific Advisory Committee to ensure the overall quality of the conference program.  

If you are interested in presenting, pleas click here to submit a speaking proposal for review.

Deadline for submission is April 24, 2015.  

We truly welcome your comments, suggestions and speaker referrals as we shape the program.

For more details on the conference, please contact:
Marina Filshtinsky, M.D.
Senior Director, Conferences
Cambridge Healthtech Institute
Phone: 781-972-5496
Email: mfilshtinsky@healthtech.com 

For exhibit & sponsorship information, please contact:
Carolyn Benton
Business Development Manager
Cambridge Healthtech Institute
Phone: 781-972-5412, Fax: (781) 972-5470
email: cbenton@healthtech.com  

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