DAY 3: THURSDAY, OCTOBER 30
7:30am Morning Coffee and One-to-One Meetings
8:45 Chairperson’s Opening Remarks & Review of Day Two
DATA INTEGRATION TOOLS
9:00 CASE STUDY: Community-Based Collaborative Drug Discovery for Neglected Infectious Diseases and Cancer
A community-based platform is currently being used openly to help develop new treatments for neglected infectious diseases such as malaria, Chagas Disease, and African Sleeping Sickness and securely against commercial cancer targets. This new collaborative technology allows researchers to build up networks of technical experts around therapeutic or target areas, thus facilitating discovery of new drug candidates. Case studies from scientists working in open and secure collaborative groups to rapidly develop drug candidates for commercial and humanitarian markets will be presented.
Sean Ekins, M.Sc., Ph.D., D.Sc., Collaborations Director, Collaborative Drug Discovery, Inc.
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9:45 CASE STUDY: Making Open Access Instrumentation Open to All
Screening processes are expensive. Some companies utilize outsourcing for their screening processes. By doing so, they lose control over the process utilized to make measurements on their compounds, as well as put their intellectual property at risk. In-house screening capability is a must for certain chemical entities, and costs can be controlled by allowing sharing of instrumentation across therapeutic areas. Screen sharing allows in house measurements to be taken, whereas before cost factors prohibited them. Attendees will learn potential solutions available to create a user interface between a customer (chemist) and an instrument (assay), allowing a wide variety of scientists with varying skill sets to independently utilize and run the screening processes they require for their projects.
Brian Bissett, M.B.A., M.S.E.E., Scientist, Exploratory Medicinal Sciences, Molecular Properties Group, Pfizer, Inc.
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10:30 Applying Knowledge Engineering to Pathways: Semantics in Pharma R&D
Ted Slater, M.A., M.S., Senior Manager, Pfizer Worldwide Technologies
Anders Berglund, Ph.D., Principal Scientist, Pfizer Global Research and Development
11:15 KEYNOTE PRESENTATION: An IT Framework for Collaborative Digital Discovery and Development
David Medina, Director, WW Pharma and Life Sciences, Hewlett-Packard Company
The pharma industry is highly interested in genomic-based medicine and the potential of personalized medicine. At present there are a wide variety of point solutions available, both commercial and open source, but no standard, easy to deploy framework which can be used to integrate these various point solutions. This presentation will present a collaborative platform for bioinformatics used in bioresearch based on a scalable, standards-based, easy-to-deploy, SOA-based architecture. This platform will facilitate the integration of intra-organizational research efforts and enable inter-organizational R&D collaboration. The platform will also enable pharma R&D organizations to effectively access disparate data sources and enable the cross-analysis of genomic, proteomic and clinical data. This research platform could enable the next generation of clinical research initiatives by providing a standards-based technology infrastructure allowing for much-needed commonality amongst research institutions that will enable easier collaboration between research partners as well as increase the effectiveness of their research efforts.
12:00 Close of Conference