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Biobank book

Published March 2009

The Future of Biobanks:
Regulation, ethics, investment and
the humanization of drug discovery

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FFPE and RNA Extraction

Published Genome Technology July 2009

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Advances in Gene
Expression Profiling
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The Science of BioBanking

Advances in molecular
high-throughput assays for gene expression (DNA/RNA) signatures have generated the parallel need for well annotated properly preserved biospecimens. Samples from both diseased and unaffected normal tissues are often required. Like traditional banks, biobanks are meant to be used and are most useful when the needs of end-users (researchers) are considered. Thus, a well managed biobank is a critical prerequisite for high-quality biological research. Cambridge Healthtech Institute’s Inaugural The Science of Biobanking is uniquely designed to explore the critical interactions between bioDEPOSITORS, bioBANKERS, and bioRECIPENTS who are all invested in the future of bioMOLECULAR research.

Session Topics Include:

  • Comprehensive BioBanking: The Specimen Life Cycle
  • Defining and Utilizing Biospecimens with an Eye for Fit-for-Purpose
  • Profiling Gene Expression from Tissue



Carolyn Compton, M.D., Ph.D.
Director, Biorepositories & Biospecimen Research
National Cancer Institute

Elizabeth Mansfield, Ph.D.
Director, Personalized Medicine Staff, Office of In Vitro Diagnostic Devices


Pre-Conference Short Course* – Sunday, November 15

2:00 - 5:00 pm Scientific & Technical Considerations for Development & Managing Biobanking Protocols

The biospecimen research protocol is the cornerstone of any research utilizing precious biological samples and serves as a crucial tool to support both large and small biobanking programs.  Determining the quality of biological specimens continues to be a significant challenge for all research programs as investigators struggle to delineate biological change from specimen artifact.  Both financial and specimen management are interrelated components of any archival strategy which require careful management to ensure the quality and accessibility of renewable and more importantly, non-renewable biological resources.  The management of biorepository protocols is one of the largest and most important considerations when calculating costs in biobanking programs today, putting sustainable quality operations of biospecimen resources at risk.  While often overlooked, proactive management and design of biobanking protocols can dramatically improve & address critical issues helping most programs achieve the quality required for serving their community.  This workshop will present an in-depth overview and discussion of the following topics:

  • Recommended Practice for Protocol Development
  • Considerations for Evidence-based Protocol Design
  • Factors related to Downstream Analysis
  • Operational Strategies for Management of End User Protocols
  • Guidelines to Optimize IRB Review
  • Issues Related to Culling & Disaster Planning and Financial Considerations & Cost Use Cases

Who Should Attend? 
Biospecimen Resource Directors, Lab Managers, Technicians,  Scientists & Biobank End Users, Regulatory & Informatics Professionals and Policymakers & Grant Writers/Managers

Course Instructors: 
Andrew Brooks, Ph.D., Director, Bionomics Research & Technology, Rutgers University Cell and DNA Repository, RUCDR

Lisa Miranda, President, Biobusiness Consulting Inc.; Former Technical Director, TTAB Core Facility, University of Pennsylvania

* Separate registration required

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