CONFERENCE SERIES: Informatics & IT
Recorded at: XGen Congress
Digital Course: Data Management and Storage: The Next Hurdle for NGS
March 15, 2010
About this Product:
This introductory digital course, co-organized by The BioTeam and CHI, is intended to provide in-depth, interactive guidance on the essential do’s and don’ts in coping with the prodigious volumes of data produced in next-generation sequencing. This course will focus on the application of new technologies to enable Pfizer’s DNA research.
About the Conference:
Now-generation sequencing platforms are capable of generating gigabytes of data in a sequence run, leading to terabytes of data in a single experiment. Thus, data storage, transfer, and analysis unquestionably will be the rate-limiting steps in turning this new sequencing data into knowledge. Sequencing Data Analysis and Storage convenes engineers who are developing the sequencing platforms, biological researchers who are designing and running the experiments, biostatisticians who are analyzing and interpreting the data, and software developers who are managing and storing the data. Each specialty provides unique perspectives and must be integrated into a cohesive, comprehensive team to decipher the sequencing data deluge.
Agenda at a Glance:
The explosion in demand for next-generation sequencing platforms brings with it a monumental challenge for any research group, organization or facility in setting up the pipeline and infrastructure to handle and manage the torrent of data about to be unleashed. These challenges are only intensifying as labs audition and integrate new platforms, expand capacity, and try to balance a growing array of projects, users and applications. This introductory short course, co-organized by The BioTeam and CHI, is intended to provide in-depth, interactive guidance on the essential do’s and don’ts in coping with the prodigious volumes of data produced in next-generation sequencing. This workshop will focus on the application of new technologies to enable Pfizer’s DNA research.
Topics include:
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Building the IT infrastructure, software and LIMS to handle sequencing data
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Strategies for data storage, quality control and analysis
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Needs, design, and maintenance for massive storage and back-up
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Methods for archiving and managing the life cycle of data
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Cost control
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Cloud computing
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Using WIKI technology
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Storage and data management technologies
Course participants are encouraged to share their challenges and bring specific data storage requirements. Ample time will be given for interactive discussion. This collegial atmosphere will encourage productivity from your NGS investment. This course is designed for researchers who have made a NGS platform purchase(s) or are considering one in the near future.
Instructors:
Chris Dagdigian, Founding Partner & Director of Technology, BioTeam, Inc.
Biography: Formerly of Blackstone Computing and Genetics Institute, Dagdigian specializes in research computing and infrastructure technology issues in the life sciences. A supporter of free software and open standards for life science research, he is a founding member of the Bioperl Project, co-founder of the Bioclusters mailing list and serves on the board of directors as Treasurer of the Open Bioinformatics Foundation. While at Blackstone, Dagdigian was project manager and technical lead for the creation and integration of the Vertex Pharmaceutical VAMPIRE cluster, which replaced an existing Top500 supercomputer used for cutting edge discovery research and informatics. Dagdigian received his bachelor’s degree from Worcester Polytechnic Institute (WPI) in Biotechnology and occasionally finds the time to continue his graduate coursework at Harvard Extension School.
Giles Day, Senior Director, BBC Informatics, Pfizer Global R&D
Biography: Giles joined Pfizer in 1995 from Manchester University’s School of Biological Sciences, where he completed a BSc in Biology and a MSc in Computational Biology. He spent 5 years at Pfizer UK helping to establish Bioinformatics as a discipline, building the technical infrastructure for genomic analysis and working on a number of Therapeutic Area programs, specializing in Antifungals.
In 2000 Giles moved to the then Discovery Technology Center in Cambridge, MA and the Research Informatics group, becoming Director of the group in 2004. At RTC Giles led a small but highly talented team focused on bringing new technologies and innovations to the wider Pfizer organization. Developments and applications identified by the team have been transformational to Pfizer’s informatics and research processes.
Following his role in Cambridge, Giles spent a year leading the Target & Mechanism Informatics group, specializing in developing systems to aid target selection and analysis, before moving to become head of informatics for Pfizer’s new research division, the Biotherapeutics and Bioinnovation Center (BBC) based in San Francisco.
Jacob Glanville, Research Informatics Developer, BBC Informatics, Pfizer Global R&D
Biography: Jacob has been a Research Informatics Developer at Pfizer since 2008. Before joining Pfizer, he was a Bioinformatics Technician at Berkeley Phylogenomics Group, where he specialized in bioinformatic infrastructure development, system administration, and web development. Jacob was educated at the University of California, Berkeley.
Adam Kraut, Scientific Consultant, BioTeam, Inc.
Biography: Adam Kraut is a Scientific Consultant for BioTeam trained in Information Science at the University of Pittsburgh. He went on to study Computational Biology at Carnegie Mellon University. As a researcher at the Pittsburgh Supercomputing Center and National Resource for Biomedical Supercomputing, he developed new methods for protein structure prediction to compete in multiple rounds of CASP. While at the PSC he also contributed to core projects in biomolecular simulation, enzyme design, and multi-scale modeling. In addition to high-performance computing support and software development, Kraut brings practical experience in structural bioinformatics and macromolecular modeling to the BioTeam.
About this Product:
4 Presentations
Over 160 slides
161 minutes
Single Copy - $345.00
Site License - $1,380.00