Cell-based Label-free Binding Affinity and Kinetics Using Surface Plasmon Resonance Microscopy Technology  
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November 6, 2019
1 pm to 2 pm EDT



Webinar Description:

Surface Plasmon Resonance (SPR) is a widely used label-free detection technique for studying binding interactions of biomolecules. One of the most significant SPR developments in recent years is SPR Microscopy (SPRM), a powerful technology that combines cell culture and imaging techniques with biophysical assays. This new technology enables measurement of real time and label-free binding interactions in physiological conditions thus providing direct and more relevant information about the binding events.

Learning Objectives:

  • Understand principles of SPRM
  • See application examples developed with Pfizer, AstraZeneca, and others
  • Learn from Prof. Nongjian “NJ” Tao about SPRM studies of drug to cell membrane proteins such as HER2 (human epidermal growth factor receptor 2) and Herceptin interactions.
  • Detection of single exosomes using an enhanced SPRM set up will be briefly discussed.


Shijie Wu image

Shijie Wu, PhD
Application Scientist
Biosensing Instrument

Dr Wu has over 15 years of experience developing applications of award-winning technologies and an author of over 100 peer reviewed publications/application notes and 2 books. He has a PhD in Physical Chemistry from University of Guelph and BS in Chemistry from Nankai University.

Nongjian “NJ” Tao image

Nongjian “NJ” Tao, PhD
Center Director and Professor, Biodesign Center for Bioelectronics and Biosensors
Arizona State University

Prof Tao’s expertise lies in molecular electronics and nanoelectronics, chemical and biological sensors, and wireless devices for mobile health and environmental applications. Tao’s research center explores fundamental properties of single molecules and develops new sensing and detection technologies. In recent years, he has pioneered many applications using SPRM technology.


Cost: No Cost!