March 31, 2016

Sponsored by
Unchained Labs Logo



Webinar Description:

Nail Down Your Best Formulations Using Thermal Stability Screening. Your drug is worthless unless it is stable and in a good formulation. We’ll talk about the UNit, an instrument that ranks the biologic stability in a variety of ways. The UNit uses intrinsic fluorescence and static light scattering to rank order proteins based on when they unfold and when they aggregate. The system uses extremely low sample volumes (9 µL) and can measure up to 48 samples simultaneously. Quickly get your answers and move on with your best formulations or conditions. Discussions will include formulation design for mAbs, ADCs, VLPs and subunit vaccines.

Learning Objectives:

  • Learn how thermal stability ranking speeds up formulation development
  • See the application of thermal stability ranking in multiple therapeutic areas
  • Learn how one platform can be used multiple ways to characterize biologics


Joe Barco, PhD

Director, Product Marketing

Unchained Labs

Joe Barco is the Director of Product Marketing at Unchained Labs. He is responsible for new product launches and product development for protein analytical tools. Joe received his PhD in Chemistry from Stanford University. He has spent 15 years in the biotechnology instrumentation arena, first as an applications scientist, followed by positions of increasing responsibility in product management and marketing. His main interest is bringing better tools to scientific discovery.

Pradyot Nandi, PhD

Research Investigator

Bristol-Meyers Squibb, Co.

Pradyot Nandi works for the Candidate Optimization group of Bristol-Myers Squibb, Co. (BMS) in Lawrenceville, NJ in the early development of biologics formulation. Pradyot received his PhD in Pharmaceutical Chemistry from the University of Kansas followed by postdoctoral training in University of Colorado Center for Pharmaceutical Biotechnology. He has published several peer reviewed articles, books and a patent application with citation count of 450+. His research interests include formulation development and analytics for vaccines, proteins, monoclonal antibodies and antibody drug conjugates to optimize stability and manufacturability.