May 17, 2016
11 am to 12 pm EDT

Sponsored by
Unchained Labs Logo



Webinar Description:

Meet Our UNcle: the All-In-One Biologics Stability Platform. Characterizing biologic stability is a wrestling match with disjointed data from sub-optimized tools. Not anymore. A better approach is to use one platform that can make multiple measurements from the same sample. Our UNcle combines fluorescence, SLS, and DLS reads in one instrument. This combination allows you to quickly and efficiently characterize all the size, aggregation, thermal ramp, isothermal and viscosity information you want. As many as 48 protein constructs and formulations can be run simultaneously, and applications that use multiple detection methods let researchers grab many of these measurements at the same time. We’ll talk about unique approaches to formulation and construct characterization and how you can do them all with way less sample than before.

Learning Objectives:

  • See how thermal stability ranking speeds up formulation development
  • Learn how low volume, high-sensitivity DLS can enable quick and easy determinations of stability
  • Find out how multi-mode detection enables more creative and sample-saving approaches to protein characterization
  • Meet the one platform that can be used to measure the melting temperature, aggregation onset, isothermal stability, B22, kD and viscosity of biologics

Who Should Attend:

  • Scientists who want to quickly rank proteins and formulations
  • Scientists who need more flexibility in how they characterize their proteins
  • Scientists interested in tools to screen for biologic stability
  • Anyone interested in formulating better biologics with less sample


Krista WitteKrista Witte, PhD.

Vice President, Product Development

Unchained Labs

Krista loves building assays and analytical tools to do great science. She has over 15 years of experience in life sciences instrumentation and application development. Prior to joining Unchained Labs, Krista was a founding team member of ForteBio, now Pall ForteBio. In her decade at the company, she held many roles including heading up Applications, Assay Development, System Integration, QC and R&D. She saw the company from angel-funded start-up to a leading provider of label-free instrumentation. Prior to ForteBio, Krista headed up the Applications team at Zyomyx, taking a lead role in developing their protein microarray technology. Krista holds a Ph.D. in Carbohydrate Chemistry from The Scripps Research Institute and a B.S. in Chemistry from Texas A&M.


Taegen ClaryTaegen Clary

Vice President

Unchained Labs

Taegen has over 15 years of experience using and marketing enabling life science instrumentation and consumables. As the Director of Pharmaceutical Segment Marketing at Agilent Technologies, he led the marketing organization focused on the company’s largest customer segment, which has experienced consistent, above-market growth rates and 2014 sales revenues of $1B. Over his 7 years at Agilent, Taegen was the Product Manager for Proteomics and Protein Chemistries and also led the Life Science group’s efforts in the area of protein therapeutics. He began his career at Berlex Biosciences, now a part of Bayer Healthcare, running mass spectrometers and developing assays to measure drug passage across the blood brain barrier. Taegen has an M.B.A. in Marketing from St. Mary’s College of California and a B.S. in Biotechnology from the University of California, Davis.