Friday, October 16, 2020 10:00 AM | 1:00 PM

Lead Instructor: Joe Rucker

Joseph Rucker, PhD, Vice President, Research and Development, Integral Molecular, Inc.

Joe Rucker is the Vice President of Research & Development, a co-founder of Integral Molecular and an inventor of Integral Molecular’s founding Lipoparticle technology. Since joining the company, he has led the development of new applications for Lipoparticle technology, including its use in generating novel antibodies against membrane proteins. Dr. Rucker earned his PhD from the University of California, Berkeley and completed postdoctoral studies at the University of Pennsylvania.

Workshop Description

This training is directed to research scientists and service/reagent providers working in the discovery and development stages for biotherapeutics with potential applications against membrane protein targets.

Who Should Attend

This training is directed to research scientists and service/reagent providers working in the discovery and development stages for biotherapeutics with potential applications against membrane protein targets.

1. Overview of different classes of membrane proteins including structure, mechanism, and their role in disease
2. Antigen preparation methods
3. Methods for antibody isolation
4. In vitro assays for antibody characterization
5. Review of mechanisms relevant to complex membrane proteins
• GPCRs
• Ion channels
• Transporters
6. Review and Case Studies of complex membrane protein-targeting antibodies in discovery and development